Heart phenotypes in tupisl-1 mutants.
(A,B,D-J) Compared with wild-type Drosophila
embryos, tupisl-1 mutants are characterized by gaps in
expression of all examined myocardial (Dmef2 and Tin) and all pericardial (Pc,
Odd and Eve) cell markers. (C,K) Embryos that are
transheterozygotic for tupisl-1 and a deficiency that
includes the tup locus, Df(2L)OD15, also show gaps in Dmef2
expression at stage 14 (arrows in C) and show a strong reduction of
Tin-expressing cardiac cells at late stage 11 (asterisk in K). Arrowheads in K
point to Tin-positive visceral mesodermal cells. as, amnioserosa; rg, ring
glands.