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. 2009 Jun 3;4(6):e5773. doi: 10.1371/journal.pone.0005773

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Lehmann et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(a) Synthetase with cognate tRNA (structure 1ZJW from Protein Data Bank). (b) Kinetic scheme of the elementary translation process. Two types of tRNAs (complementary to two template codons) are unselectively loaded with two types of amino acids (the rates of loading are only concentration-dependent). The grey rugby ball is a stabilizing cofactor (see text for explanations). (c) Characteristic regimes of the polymerization process.