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| Passage Series | Total number of mutations±SE | |
| Uncloned viruses | Cloned viruses | |
| HuH-7 only | 5.25±0.25AB * | 2.45±0.48A |
| Alternating | 7.00±0.82A | 2.00±0.41A |
| C6/36 only | 3.75±0.85B | 1.26±0.63A |
*: Superscripted letters indicate the results of a Tukey-Kramer post-hoc test. Uncloned and cloned viruses were analyzed separately. Values that do not share a letter are significantly different.
