Table 10. Summary of non-synonymous mutations and mutations in the non-coding regions (NCR) that occurred in more than one passage series.

Mutation	ENDEMIC: Cloned						ENDEMIC: Uncloned						SYLVATIC: Cloned						SYLVATIC: Uncloned
	H7-A	H7-B	Alt-A	Alt-B	C6-A	C6-B	H7-A	H7-B	Alt-A	Alt-B	C6-A	C6-B	H7-A	H7-B	Alt-A	Alt-B	C6-A	C6-B	H7-A	H7-B	Alt-A	Alt-B	C6-A	C6-B
G1120A																				Xa	Xa	Xx
G1539A	X			X				X	X	X
G1539R		Xa					Xa
T2030C													X	X
T4471C					X	X					X	X
A7416G							X	X
G9179C																				X		X
G9179S																					Xb		Xb
T10392Cc								X	X	X	X	X
T10400Cc															X		X			X	X	X
G10422Tc																X		X

^aMutation occurred as a G/A mixture.

^bMutation occurred as a G/C mixture.

^cMutation present in the 3′-NCR of the genome.

Abbreviations: H7-A, H7-B – Huh-7 – passaged DENV; C6-A, C6-B – C6/36-passaged DENV; Alt-A, Alt-B – alternate-passaged DENV.