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. 2009 Jun 3;4(6):e5775. doi: 10.1371/journal.pone.0005775

Table 3. Common regulators and targets of differentially expressed genes (from Table 1) identified by Pathway Studio 5 analysis.

Regulators Targets
Small molecule Small molecule
androgen androgen
Ca2+ androstenedione
cAMP Ca2+
cholesterol cAMP
dexamethasone ceramide
estradiol cholesterol
estrogen cortisol
fatty acids estradiol
glucocorticoid estrogen
glucose fatty acids
norepinephrine glutamate
phospholipids lipid
progesterone melanin
RA NO
siRNA progesterone
steroids testosterone
testosterone tyrosine
Disorders Disorders
diabetes mellitus Crohn disease
fetal development dementia
inflammation diabetes mellitus
neural tube malformation digestion
neuroblastoma embryonic cell viability
endocrine abnormality
endocrine function
epilepsy
fetal development
hyperandrogenemia
hyperinsulinemia
inflammation
long-term potentiation
muscular dystrophy
neural tube malformation
neuron dysfunction
neuron toxicity
peripheral nerve function