Table 1. Percent identities of the nucleotide coding sequences of selected HAdV-D53 proteins and their homologs^a.

	HAdV-D8pb	HAdV-D19	HAdV-D22	HAdV-D37	HAdV-D48	HAdV-D49
E1B 19K	94.9	99.3	99	99.5	97.8	97.8
E1B 55K	96	99.2	98.3	99.3	97.4	96.9
IX	95.1	96.1	98.5	96.1	97.1	97.1
IVa2	96.7	98	97.4	98	98.3	91.3
DNA polymerase	95.2	98.1	97.6	98	98	98
pTP	93.3	97.6	96.8	97.9	96.4	96.8
52K	95.7	98	98.1	100	97.9	98.3
penton base	89.2	91.2	92.4	100	90.5	90.1
pVII	79.2	80.4	80.4	83.2	80	80.1
V	85.2	87	87.5	87.2	87.7	87.3
pX	95.1	100	100	100	98.7	99.6
hexon	89.4	90.2	98.4	90.5	90.6	90.4
protease	95.4	96	95.4	99.8	96.5	96.5
22K	89.9	100	98.8	100	99.3	99
pVIII	95.6	98.4	98.5	98.4	98.3	97.7
12.2K	93.2	96	97.5	96	96.9	96.9
CR1-α	52.5	80.5	97	80.5	75.4	77.6
18.4K	95.2	91.1	98.1	91.1	96.2	94.1
CR1-β	100	74.5	85.1	74.5	64.5	58
CR1-γ	86.4	75.3	Ndc	75.3	75.1	80.5
RID-α	93.5	94.2	94.2	94.2	98.2	98.2
RID-β	90.6	87.4	93.2	87.4	94.2	99.2
14.7K	96.7	95.2	97.2	95.2	96.7	97.7
fiber	100	75.1	67.6	75	69	67.6
dTPase	100	48.4	88.9	48.4	85.1	85

Standard nomenclature has been applied so that orthologs have the same name (Davison et al., 2003). Numbers in bold reflect the proposed origin. Italics note the gene with supposed double origin.

^aPercent identities and similarities were determined by global alignment using the EMBOSS needle program with a gap penalty of 10.0 and a gap extension penalty of 5.0.

^bNot present in the genome.

^cPrototype HAdV-D8 strain is Trim isolate – ATCC VR-1604.