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. 2009 May;67(5):503–510. doi: 10.1111/j.1365-2125.2009.03393.x

Table 6.

Effects of CYP2C19 genotype and clarithromycin resistance on the eradication rate

EM PM

Group H. pylori eradication * HomEM HetEM All EM p-value (HomEM, HetEM, PM)
A S 4 (0) 6 (1) 10 (1) 2 (0) 0.99
F 1 (1) 2 (1) 3 (2) 1 (1)
B S 4 (0) 3 (0) 7 (0) 4 (0) 0.17
F 1 (0) 4 (0) 5 (0) 0 (0)
C S 5 (0) 6 (0) 11 (0) 2 (0) 0.60
F 2 (1) 0 (0) 2 (1) 0 (0)
*

S, Success; F, Failure.

The values in parentheses indicate the number of subjects infected by clarithromycin-resistant H. pylori. HomEM, homozygous extensive metabolizers; HetEM, heterozygous extensive metabolizers; EM, extensive metabolizers; PM, poor metabolizers.