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C-terminal truncations, internal deletions and single or combinatory point mutants were bioengineered to evaluate their impact on the subcellular distribution patterns of mouse PXR. CFP, Cyan Fluorescent Protein; YFP, Yellow Fluorescent Protein; DBD, DNA Binding Domain; LBD, Ligand Binding Domain. CFP-mPXR431 is the non-mutated wild-type form of murine PXR.
