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. 2009 May 8;7:e004. doi: 10.1621/nrs.07004

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Copyright © 2009, Matic et al. This is an open-access article distributed under the terms of the Creative Commons Non-Commercial Attribution License, which permits unrestricted non-commercial use distribution and reproduction in any medium, provided the original work is properly cited.

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Ranges of subcellular distribution categories were identified (see Figure 2) in a number of cells. Categories indicating decreased cytoplasmic presence of the mutant (with reference to the control) were not identified. Investigations were carried out in both control and ligand-treated mice. Categorical counts are represented as percentage of the total number of cells exhibiting a single CFP reference state (i.e., N, N>C or N=C) based on cell number. YFP-mPXR_{R63/64/88/89A}, YFP-mPXR_{Δ171-211, R63/64/88/89A} and YFP-mPXR_L386X showed a substantial alteration in the subcellular distribution, indicative of impaired intracellular localisation ability.