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. 2009 Jun 3;4(6):e5777. doi: 10.1371/journal.pone.0005777

Table 1. Expression levels of mitochondrial fission and fusion factors in Pink1 −/− tissue.

Taqman® assay mitochondrial function gene symbol liver 2 days brain 2 days liver 18 months brain 18 months
Mm00612599_m1 fusion MfnI ns ns ns ns
Mm00500129_m1 fusion MfnII ns ns ns ns
Mm00453879_m1 fusion OpaI ns ns ns ns
Mm00481580_m1 fission FisI ns ns ns ns
Mm01342903_m1 fission DrpI ns ns ns ns
Mm00466042_m1 fission Mtp18 red. 25%; p = 0.04 red. 10%; p = 0.09 red. 30%; p = 0.0002 ns

A selective reduction of the fission factor Mtp18 mRNA levels in qPCR analysis was consistently significant at ages 2 days and 18 months for the particularly mitochondria-rich and homogeneous liver tissue, while the effect missed significance for the mixed tissue brain.

red. = reduced by factor; ns = non-significant.