Table 1.
Cutaneous lymphomas diagnosed during 2001-2005 in the 16 SEER program registries by histologic type and sex
| ICD-O-3*codes | Total |
Frequency by |
Male |
Female |
M/FIRR | P | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Cases | Frequency, % | Cell type, % | Rate† | Cases | Rate | Cases | Rate | ||||
| Total | 9670-9728, 9827 excluding 9675, 9721 | 3884 | 100.0 | 10.7 | 2285 | 14.0 | 1599 | 8.2 | 1.72 | < .001 | |
| Mature T-cell and NK-cell neoplasms (CTCLs) | 2769 | 71.3 | 100.0 | 7.7 | 1626 | 10.0 | 1143 | 5.9 | 1.70 | < .001 | |
| Mycosis fungoides (MF) | 9700 | 1487 | 38.3 | 53.7 | 4.1 | 868 | 5.3 | 619 | 3.2 | 1.66 | < .001 |
| Sézary syndrome (SS) | 9701 | 33 | 0.8 | 1.2 | 0.1 | 20 | 0.1 | 13 | 0.1 | 2.11 | .05 |
| CD30+ T-cell lymphoproliferative disorders of the skin (CD30+ LPD) | 9714, 9718 | 396 | 10.2 | 14.3 | 1.1 | 233 | 1.5 | 163 | 0.8 | 1.73 | < .001 |
| Subcutaneous panniculitis-like T-cell lymphoma (SPTCL) | 9708 | 23 | 0.6 | 0.8 | 0.1 | 6 | ∼‡ | 17 | 0.1 | ∼ | ∼ |
| Primary cutaneous peripheral T-cell lymphoma (pcPTL) | 9702, 9709 | 809 | 20.8 | 29.2 | 2.2 | 485 | 3.0 | 324 | 1.7 | 1.82 | < .001 |
| Extranodal NK/T-cell lymphoma, nasal type | 9719 | 12 | 0.3 | 0.4 | 0.0 | 9 | ∼ | 3 | ∼ | ∼ | ∼ |
| Adult T-cell leukemia/lymphoma (HTLV-1 pos) | 9827 | 2 | 0.1 | 0.1 | ∼ | 2 | ∼ | 0 | ∼ | ∼ | ∼ |
| Angioimmunoblastic T-cell lymphoma | 9705 | 7 | 0.2 | 0.3 | ∼ | 3 | ∼ | 4 | ∼ | ∼ | ∼ |
| Mature B-cell neoplasms | 1105 | 28.5 | 100.0 | 3.1 | 651 | 4.0 | 454 | 2.3 | 1.76 | < .001 | |
| Cutaneous marginal zone B-cell lymphoma (pcMZL) | 9699 | 274 | 7.1 | 24.8 | 0.8 | 161 | 1.0 | 113 | 0.6 | 1.28 | .001 |
| Cutaneous follicle center lymphoma (pcFCL) | 9690, 9691, 9695, 9698 | 331 | 8.5 | 30.0 | 0.9 | 200 | 1.2 | 131 | 0.7 | 1.84 | < .001 |
| Cutaneous diffuse large B-cell lymphoma (pcDLBCL) | 9680, 9684 | 443 | 11.4 | 40.1 | 1.2 | 252 | 1.6 | 191 | 0.9 | 1.70 | < .001 |
| pcDLBCL-leg | 9680, 9684 | 101 | 2.6 | 9.1 | 0.3 | 45 | 0.3 | 56 | 0.3 | 1.19 | .44 |
| pcDLBCL-other | 9680, 9684 | 342 | 8.8 | 31.0 | 1.0 | 207 | 1.3 | 135 | 0.7 | 1.90 | < .001 |
| Extracutaneous lymphomas involving the skin | 9670, 9671, 9673, 9687 | 57 | 1.5 | 5.2 | 0.2 | 38 | 0.2 | 19 | 0.1 | 2.55 | .001 |
| Small lymphocytic lymphoma | 9670 | 32 | 0.8 | 2.9 | 0.1 | 21 | 0.1 | 11 | 0.1 | 2.44 | .024 |
| Lymphoplasmacytic lymphoma | 9671 | 9 | 0.2 | 0.8 | ∼ | 4 | ∼ | 5 | ∼ | ∼ | ∼ |
| Mantle cell lymphoma | 9673 | 12 | 0.3 | 1.1 | 0.0 | 10 | 0.1 | 2 | ∼ | ∼ | ∼ |
| Burkitt lymphoma | 9687 | 4 | 0.1 | 0.4 | ∼ | 3 | ∼ | 1 | ∼ | ∼ | ∼ |
| Immature hematologic neoplasms | 9727, 9728 | 10 | 0.3 | 100.0 | 0.0 | 8 | ∼ | 2 | ∼ | ∼ | ∼ |
| Blastic NK-cell lymphoma | 9727 | 6 | 0.2 | 60.0 | ∼ | 6 | ∼ | 0 | ∼ | ∼ | ∼ |
| Precursor B-cell lymphoblastic lymphoma | 9728 | 4 | 0.1 | 40.0 | ∼ | 2 | ∼ | 2 | ∼ | ∼ | ∼ |
pc indicates primary cutaneous.
*
ICD-O-3 CODES 9699, 9708, 9718, 9719, 9727, and 9728 are new and were not included in ICD-O-2.
†
Rates are per 1 000 000 person-years and age-adjusted to the 2000 US standard population (19 age groups; Census P25-1130).
‡
Statistic not shown, based on fewer than 10 cases.