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. 2009 Feb 25;4(2):111–118. doi: 10.1093/scan/nsn043

Table 2.

Whole-brain search for regions showing activity within the Oe–Oc contrast that correlated with empathic concern and/or perspective taking

Region L/R Peak voxel coordinates t-scores
Positive correlation with empathic concern
    Middle temporal pole R 33, 3, −39 2.98
    Dorsal anterior cingulate L −9, 12, 21 2.84
    Middle temporal cortex L −45, −21, −18 2.72
    Middle temporal cortex L −48, −3, −30 2.66
    Ventral anterior cingulate L −12, 30, −9 2.16
    Ventral anterior cingulate/medial  frontal cortex R −3, 33, −12 1.93
Negative correlation with empathic concern
    Supplementary motor area L −9, −12, 72 3.25
    Superior frontal cortex L −15, 21, 66 2.78
    Orbitofrontal cortex L −21, 57, 6 2.70
    Calcarine R 21, −102, 6 2.64
    Parahippocampal gyrus L −3, −6, −21 2.60
Positive correlation with perspective taking No regions reached threshold
Negative correlation with perspective taking
    Parahippocampal gyrus R 15, −15, −30 3.99
    Parahippocampal gyrus L −18, 0, −27 3.63
    Cerebellum R 6, −21, −48 3.42
    Caudate L 0, 3, −15 3.42
    Vermis L −6, −45, −30 3.31
    Fusiform R 27, −33, −18 3.22
    Parahippocampal gyrus R 36, −42, −6 3.19
    Fusiform L −27, −48, −12 3.18

Bolded regions small volume corrected, p < 0.05, for 10 mm sphere around the following coordinates: Ventral ACC coordinates: x = 3, y = 23, z = −8. All other activations p < 0.001, uncorrected for whole-brain volume.