Table 1.

List of brain regions showing a significant interaction effect of condition (fearful/happy vs neutral facial expressions) and drug (reboxetine vs placebo) (P < 0.001, uncorrected; voxel extent threshold >5)

Contrast	Region	Side	k	MNI-coordinates			T
				x	y	z
(Fear > Neutral) Reboxetine > (Fear > Neutral) Placebo
	Heschl's gyrus	R	33	50	−16	8	4.16
	Inferior frontal gyrus	R	33	42	42	−10	3.97
	Fusiform gyrus	R	26	32	−60	−14	3.87
	Precuneus	R	26	20	−54	44	3.85
	Lingual gyrus	R	22	18	−86	−4	3.89
	Fusiform gyrus	L	15	−36	−56	−8	3.91
	Inferior frontal gyrus	L	13	–22	30	−12	3.71
	Angular gyrus	R	12	54	−50	30	3.65
	Supramarginal gyrus	L	11	−48	−44	32	3.63
	Hippocampus/Amygdala	R	8	26	6	−32	3.27
	Supramarginal gyrus	R	7	60	−24	22	3.56
(Happy > Neutral) Reboxetine > (Happy > Neutral) Placebo
	Supramarginal gyrus	L	42	−46	−40	30	3.66
	Caudate nucleus	L	38	−18	−4	26	4.11
	Cerebellum	R	33	16	−64	−34	3.96
	Rectal gyrus	R	27	14	28	−20	4.60
	Superior medial frontal gyrus	L	23	−12	38	28	3.76
	Superior medial frontal gyrus	L	20	−8	48	6	3.70
	Middle cingulum	R	12	12	−16	34	3.94
	Middle occipital	L	10	−32	−74	14	3.47
	Precuneus	R	8	12	−56	42	3.40
	Insula	L	6	−28	14	−10	3.34
	Middle occipital	L	6	−28	−86	42	3.33
	Cerebellar vermis	R	6	4	−68	−20	3.32