Table 2.
List of brain regions showing a significant interaction effect of condition (fearful/happy vs neutral facial expressions) and drug (placebo vs reboxetine) (P < 0.001, uncorrected; voxel extent threshold >5)
| Contrast | Region | Side | k | MNI-coordinates |
T | ||
|---|---|---|---|---|---|---|---|
| x | y | z | |||||
| (Fear > Neutral) Placebo > (Fear > Neutral) Reboxetine | |||||||
| Middle occipital gyrus | L | 29 | −40 | −74 | 24 | 3.86 | |
| Whitte matter | L | 9 | −26 | −14 | 16 | 3.55 | |
| Hippocampus | L | 7 | −12 | −28 | −6 | 3.55 | |
| Cerebellum | R | 6 | 56 | −58 | −34 | 3.54 | |
| (Happy > Neutral) Placebo > (Happy > Neutral) Reboxetine | |||||||
| Inferior temporal gyrus | R | 32 | 48 | −56 | −16 | 4.29 | |
| Superior orbital frontal gyrus | L | 20 | −18 | 54 | −10 | 3.91 | |
| Calcarine gyrus | R | 7 | 18 | −44 | 6 | 3.29 | |