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Microflow system for Br-Li exchange reaction of 2,2′-dibromobiphenyl (1). T-shaped micromixer: M1 (ø = 250 μm) and M2 (ø = 500 μm), microtube reactor: R1 and R2 (ø = 1000 μm, l = 50 cm), a solution of 2,2′-dibromobiphenyl (1): 0.10 M in THF, a solution of n-BuLi: 0.50 M in hexane, a solution of electrophile: 0.30 M in THF.
