Table 9.

Synthesis of unsymmetrially substituted biaryls from dibromobiaryls by sequential introduction of two electrophiles.^a

dibromobiaryl	electrophile	yield (%)
28	E1: MeI E2: MeOCOCl	50
		51 b
36	E1: MeI E2: PhCHO	51
		71 c
	E1: MeI E2: PhCOPh	52
		78 c

^aReactions were conducted in the microflow system shown in Figure 3 unless otherwise stated. ^bDetermined by GC. ^cIsolated yield.