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. 2009 Mar 9;184(5):707–719. doi: 10.1083/jcb.200809060

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© 2009 Berman et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jcb.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

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Figure 4. — Most mitochondrial encounters/visitations do not result in fusion. (A–C) Fluorescence microscopy images of merged (red + green) channels as described for Fig. 3. Dotted lines approximately outline the neuronal processes. Transparent arrows/lines track the same mitochondrion. (A) A mitochondrion (red, not photoactivated) moves past a yellow photoactivated mitochondrion without exchanging contents. The indicated imaging times are relative to the earliest frame shown. (B) Activated (yellow) mitochondria move past stationary/slow unactivated (red) mitochondria without exchanging contents. (C) Two adjacent/overlapping mitochondria (one photoactivated) move at similar velocities without fusing to each other or to a third stationary mitochondrion.