Figure 1.

Protease Molecule Page (top) and Substrate Molecule Page (bottom). The Protease Molecule Page shows recent news and literature of the protease (top left), known proteolytic events (top right), domain location and structure view (middle panel), as well as a cross annotation in other databases section (bottom). A graphics interface of SubstrateDB (bottom) is shown here displaying domains and experimental protease cut sites for the human amyloid β A4 protein. A total of 35 protease cut sites are filtered via selection boxes on the right. The display makes co-location of many features visible. The annotation displayed is linked back to sources (CutDB, ProteaseDB, UniProt, etc.) for more detailed annotation. The graphics display is synchronized with a text table of the same data, which can also be downloaded.