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Amount of tumor necrosis factor-alpha (TNF-α) produced by LPS-stimulated splenocytes 14 days after arthritis induction. Lyprinol® controlled the amount of TNF-α production to a level similar to the one found in rats with no arthritis, and was as effective as the NSAID Naproxen. Values shown here are mean ± SEM (n = 6). *P < 0.05.
