Figure 2.

Time course kinetics of RBCs, Hb, and Ht in peripheral blood after 5-FU injection. An experimental protocol is also shown. 5-FU (150 mg kg^–1) was injected intravenously into mice on day 0. Peripheral blood samples were collected at the indicated times, and then erythrocyte parameters were measured using an automatic hemocytometer. All tested Kampo samples were orally administered to mice once daily from days –3 to +3 after 5-FU treatment. One group of 5-FU-treated mice was treated subcutaneously with mrIL-3 (50 ng per mouse) and mrEPO (5 U per mouse). Values are presented as the mean ± SE (n = 8–11). *P < 0.05 compared to 5-FU-treated mice.