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A Gelatin zymography of MMP-2 activity of TE-13. A: Effect of nicotine on MMP-2 activity of TE-13 cells. Our study showed nicotine increased the activity of MMP-2. 1: DMSO; 2: Nicotine 100 μg/mL; 3: Nicotine 200 μg/mL; B: Effect of nimesulide on MMP-2 activity of TE-13 cells treated by nicotine. Our study showed nimesulide suppressed the effect of nicotine that increased the activity of MMP-2. 1: DMSO; 2: Nicotine 200 μg/mL; 3: Nicotine 200 μg/mL + Nimesulide 100 mmol/L.
