Table 3.
Stratification analysis of colon and rectal cancer
| Variables |
Adjusted OR (95% CI)1 |
|||||
|
Test group |
Validation group |
Merged group |
||||
| Colon cancer (n = 253) | Rectal cancer (n = 260) | Colon cancer (n = 95) | Rectal cancer (n = 98) | Colon cancer (n = 348) | Rectal cancer (n = 358) | |
| Smoking status | ||||||
| Non | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) |
| Former | 0.71 (0.34-1.49) | 1.26 (0.59-2.69) | 1.09 (0.44-2.72) | 0.41 (0.14-1.18) | 0.83 (0.48-1.43) | 0.79 (0.45-1.38) |
| Current | 1.34 (0.72-2.51) | 1.87 (0.96-3.65) | 1.03 (0.53-2.03) | 0.78 (0.40-1.51) | 1.22 (0.78-1.91) | 1.17 (0.75-1.83) |
| Drinking status | ||||||
| Non | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) |
| Former | 2.28 (0.90-5.76) | 1.32 (0.48-3.64) | 2.51 (0.78-8.06) | 3.10 (0.88-10.92) | 2.51 (1.24-5.07) | 1.71 (0.80-3.65) |
| Current | 13.24 (7.78-22.51) | 11.91 (7.14-19.87) | 3.46 (1.83-6.53) | 3.61 (1.94-6.74) | 7.60 (5.13-11.25) | 7.52 (5.13-11.01) |
| Family history of cancer | ||||||
| Negative | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) |
| Positive | 1.67 (1.01-2.75) | 1.26 (0.76-2.09) | 3.26 (1.12-9.45) | 3.52 (1.26-9.85) | 1.82 (1.17-2.82) | 1.51 (0.97-2.35) |
| BMI (kg/m2) | ||||||
| ≤ 23.9 | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) | 1.00 (ref.) |
| ≥ 24.0 | 1.48 (1.05-2.09) | 1.22 (0.86-1.73) | 1.18 (0.70-1.99) | 2.00 (1.18-3.36) | 1.38 (1.04-1.83) | 1.35 (1.02-1.79) |
1
Adjusted for age, sex, smoking status, alcohol drinking, family history of cancer, BMI.