Mitogenic and morphogenic effects of FGF-1, FGF-7, and FGF-10. (A) DNA content of E11.5 mesenchyme-free pancreatic epithelia cultured during 7 days in the absence or presence of FGF-1, FGF-7, or FGF-10 (50 ng/ml). Each data point represents the mean ± SEM of 10 pancreatic rudiments. (B-D) Effects of FGF-1 and FGF-7 on pancreatic morphogenesis in Matrigel (B) absence of exogenous FGF, (C) FGF-1, 50 ng/ml, and (D) FGF-7, 50 ng/ml.