Table 1. Clinical and laboratory data for infant with probable congenital babesiosis*.
| Clinical/laboratory data | Day of hospitalization |
|||||||
|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | |
| Maximum daily temperature, ºF | 102.7 | 101.9 | 100.6 | 98.0 | 98.8 | 99.6 | 99.4 | 98.8 |
| Hepatomegaly, cm below costal margin | 4 | 4 | 4 | 5 | Stable | Stable | Smaller | Smaller |
| Splenomegaly, cm below costal margin | 5 | 5 | 5 | 5 | Stable | Stable | Smaller | Smaller |
| Lowest daily hemoglobin level, g/dL | 8.8 | 8.1 | 7.0† | 9.8 | 8.6 | 7.4 | 8.5 | 9.6 |
| Lowest daily platelet count, 103/mm3 | 34 | 30 | 23 | 34 | 45 | 112 | 185 | 340 |
| Parasitemia, % | 15.2 | Present‡ | Present‡ | 2 | <1 | NA | 0 | NA |
| Highest daily total bilirubin level, mg/dL | 5.9§ | NA | 3.6 | 3.9 | 2.7 | 2.1 | 1.7 | 1.3 |
| Highest daily lactate dehydrogenase level, IU/L | NA | NA | 1,912¶ | 2,481 | 2,535 | 2,286 | 2,239 | 1,566 |
| Highest daily C-reactive protein level, mg/dL | 54# | NA | 130 | 82 | 62 | 39 | NA | NA |
| Treatment | CRO, ATO, AZI | CRO, ATO, AZI | CRO, ATO, AZI, PRBC | CRO, ATO, AZI | CRO, ATO, AZI | CRO, ATO, AZI | CRO, ATO, AZI | CRO, ATO, AZI |
*NA, not assessed; CRO, ceftriaxone sodium; ATO, atovaquone; AZI, azithromycin; PRBC, packed red blood cells. †Before PRBC transfusion. ‡Not quantified. §Reference range 0.1–1.2 mg/dL. ¶Reference range 313–618 IU/L. #Reference range 1.0–10.0 mg/dL.