Genetic loci of the six B. fragilis trx genes. The maps are drawn to scale; the dashed lines above the trx genes show the regions deleted in each trx mutant, and the black lines under the trx genes represent the approximate sizes of the mRNAs observed in Fig. 3. Genes: unk, unknown with no matches in database; dnaE, DNA polymerase III; fldA, flavodoxin; doxDA, thiosulfate quinone oxidoreductase; mauG, tryptophan tryptophylquinone synthesis; cztBC, heavy metal efflux pump; hel, DNA helicase; hyp-Ptase, hypothetical phosphatase; nfnB, oxygen-insensitive nitroreductase; rbr, rubrerythrin-like; per, peroxide response regulator homolog; hyp-reg, hypothetical DNA binding protein; spoU, SpoU-like RNA methylase; arsF, sulfatase.