TABLE 1.
Phenotypea and strain no. | Origin | SCCmec group | MIC (mg/liter)
|
|
---|---|---|---|---|
pH 7.4 | pH 5.5 | |||
MSSA | ||||
ATCC 25923 (β-lactamase −) | Laboratory standardb | NAg | 0.5 | 0.25 |
ATCC 11632 (β-lactamase +) | Laboratory standardb | NA | 0.5-1 | 0.25-0.5 |
NRS52 (VISA) | Clinical (bile infection)c | NA | 1 | 0.5 |
Geometric mean | 0.72 | 0.36 | ||
HA-MRSA | ||||
ATCC 33591 (inducible) | Laboratory standardb | III | 2 | 0.5 |
ATCC 33592 | Laboratory standardb | NDh | 2 | 0.5-1 |
ATCC 43300 | Laboratory standardb | ND | 1 | 0.5 |
N4120210 | Clinical (wound infection)d | I | 2 | 1 |
N4112910 | Clinical (nasal swab)d | ND | 0.5-1 | 0.25-0.5 |
N4120032 | Clinical (urinary tract infection)d | ND | 2 | 0.5 |
NRS18 (VISA) | Clinical (wound, skin and soft tissue infection)-c | II | 0.5-1 | 0.5 |
NRS126 (VISA) | Clinical (bloodstream infection)c | II | 1-2 | 0.25-0.5 |
VRS1 (VRSA) | Clinical (catheter exit site)c | II | 2 | 0.5 |
VRS2 (VRSA) | Clinical (wound infection)c | II | 1-2 | 0.5 |
Geometric mean | 1.45 | 0.43 | ||
CA-MRSA | ||||
NRS192 (PVL +) | Clinical (pneumonia, septic arthritis)c | IVa | 2 | 1 |
NRS384 (PVL +) | Clinical (wound, skin and soft tissue infection)c | IVa | 2 | 1 |
N4090440 (PVL +) | Clinical (wound infection)d | IVa | 1 | 0.5 |
N4042228 (PVL +) | Clinical (septicemia sec. to soft-tissues abscess)d | IVa | 1 | 0.5 |
STA 44 (PVL +) | Clinicale | V | 2 | 1 |
STA 268 (PVL +) | Clinicale | V | 2 | 1 |
CHU (PVL +) | Clinicale | V | 2 | 1 |
MEH2225605 (PVL +) | Clinicalf | IVa | 2 | 1 |
NRS386 (PVL −) | Clinical (bloodstream infection)c | IVa | 2 | 0.5-1 |
Geometric mean | 1.71 | 0.83 |
VISA, vancomycin intermediate S. aureus (MICs, >2 and <8 mg/liter); VRSA, vancomycin-resistant S. aureus (MICs, >8 mg/liter); PVL, Panton-Valentine leucocidin; −, negative; +, positive.
From the American Type Culture Collection.
From the Network on Antimicrobial Resistance in Staphylococcus aureus (operated by Eurofins Medinet, Inc., Herndon, VA).
Clinical collection (Y. Glupczynski, Cliniques Universitaires UCL de Mont-Godinne, Yvoir, Belgium).
Clinical collection (Y. C. Huang, Chang Gung Children's Hospital, Taiwan).
Clinical collection (L. Y. Hsu, Singapore General Hospital, Singapore).
NA, not applicable.
ND, not determined.