. 2009 Mar 16;53(6):2643–2645. doi: 10.1128/AAC.01534-08

TABLE 1.

Characteristics of aac(6′)-Ib-cr-positive isolates

Species and isolate	CIP MIC (μg/ml)	Mutation(s) in QRDRs		RAPD pattern^a	β-Lactamases	Resistance to antibiotics^b
Species and isolate	CIP MIC (μg/ml)	gyrA	parC	RAPD pattern^a	β-Lactamases	Resistance to antibiotics^b
E. cloacae
37	4	Ser83Ile	Ser80Arg	I	CTX-M-3, OXA-1	TOB, GEN, CTX, SXT
101	8	Ser83Ile	Ser80Ile	II	CTX-M-3, OXA-1	TOB, GEN, CTX, CAZ, SXT
153	8	Ser83Ile	Ser80Ile	II	CTX-M-3, OXA-1	TOB, GEN, CTX, CAZ, SXT
165	8	Ser83Ile	Ser80Ile	II	CTX-M-3, OXA-1	CTX, CAZ, SXT
E. coli
17	>16	Ser83Leu, Asp87Asn	Ser80Ile, Glu84Val	III	CTX-M-15, OXA-1, TEM-1	TOB, GEN, CTX, CAZ, SXT
24	>16	Ser83Leu, Asp87Asn	Ser80Ile, Glu84Val	III	CTX-M-15, OXA-1, TEM-1	TOB, CTX, CAZ
47	>16	Ser83Leu, Asp87Asn	Ser80Ile	IV	CTX-M-15, OXA-1	TOB, GEN, CTX, CAZ, SXT
48	>16	Ser83Leu, Asp87Asn	Ser80Ile	V	CTX-M-15, OXA-1	TOB, CTX, CAZ
125	>16	Ser83Leu, Asp87Asn	Ser80Ile, Glu84Val	III	CTX-M-15, OXA-1, TEM-1	TOB, GEN, CTX, CAZ
130	>16	Ser83Leu, Asp87Asn	Ser80Ile	IV	CTX-M-15, OXA-1	TOB, CTX, CAZ
189	>16	Ser83Leu, Asp87Asn	Ser80Ile, Glu84Val	III	CTX-M-15, OXA-1, TEM-1	TOB, GEN, CTX, CAZ
K. pneumoniae
78	1	Ser83Tyr		VI	CTX-M-15, OXA-1, SHV	TOB, GEN, CTX, CAZ, SXT
80	1	Ser83Tyr		VI	CTX-M-15, OXA-1, SHV	TOB, GEN, CTX, CAZ, SXT
110	>16	Ser83Ile	Ser80Ile	VII	OXA-1, SHV	TOB, GEN, CAZ, SXT
132	0.125			VIII	CTX-M-15, OXA-1, SHV	TOB, GEN, CTX, CAZ
135	>16	Ser83Ile	Ser80Ile	IX	CTX-M-15, OXA-1, TEM-1, SHV	TOB, GEN, CTX, CAZ, SXT
185	1	Ser83Tyr		X	CTX-M-15, OXA-1, SHV	TOB, GEN, CTX, SXT
194	16	Ser83Tyr		VI	CTX-M-15, OXA-1, SHV	TOB, GEN, CTX, CAZ, SXT
202	>16	Ser83Ile	Ser80Ile	XI	CTX-M-3, OXA-1, SHV	TOB, GEN, CTX, CAZ

RAPD, randomly amplified polymorphic DNA.

CIP, ciprofloxacin; TOB, tobramycin; GEN, gentamicin; CTX, cefotaxime; CAZ, ceftazidime; SXT, trimethoprim-sulfamethoxazole.