. 2009 Mar 23;53(6):2564–2568. doi: 10.1128/AAC.01466-08

TABLE 1.

Efficacies of known heme crystallization inhibitors

Compound	IC₅₀ for heme crystallization			IC₅₀ for P. falciparum 3D7 proliferation (nM)
	CFHCS		Phiβ assay (equivalents)^a^,^b
	μM	Equivalents^b	Phiβ assay (equivalents)^a^,^b
AMQ	67.0 ± 0.67	0.3 ± 0.001	1.45 ± 0.08	6.8 ± 2.3
CQ	374.1 ± 0.29	1.7 ± 0.003	1.91 ± 0.3	12.6 ± 2.3
MQ	476.1 ± 0.88	2.16 ± 0.004	2.90 ± 0.1	12.3 ± 2.0

Data are from reference 17.

IC₅₀ values in the Phiβ assay were reported in molar equivalents of drug to heme, a convention that allows comparisons between heme crystallization assays.