TABLE 2.
Relationship of MIC to mortality in patients with candidemia (data taken from reference 2)
| Susceptibility classification | No. of nonsurvivors/total no. in group (%) for indicated breakpoint criteria, incubation period, and growth inhibition end point |
|||||||
|---|---|---|---|---|---|---|---|---|
| Alternativea |
CLSIb |
|||||||
| 24 h |
48 h |
24 h |
48 h |
|||||
| 50% | 80% | 50% | 80% | 50% | 80% | 50% | 80% | |
| Susceptible | 17/65 (26.1) | 16/58 (27.6) | 12/55 (21.8) | 12/52 (23) | 20/74 (27) | 20/74 (27) | 18/71 (25) | 17/67 (25.4) |
| Intermediate/SDD | 3/8 (37.5) | 1/12 (8.3) | 3/11 (27.3) | 1/9 (11.1) | 0/3 (0) | 0/2 (0) | 0/3 (0) | 1/5 (20) |
| Resistant | 4/10 (40) | 7/14 (50) | 9/18 (50) | 11/21 (52.3) | 4/7 (57.1) | 4/8 (50) | 6/10 (60) | 6/10 (60) |
a
Susceptibility, MIC of <2 mg/liter; resistance, MIC of >4 mg/liter.
b
Susceptibility, MIC of ≤8 mg/liter; resistance, MIC of ≥64 mg/liter.