FIG. 2.
Pulmonary infiltrate volume determined by image analysis of serial CT scans of untreated controls (Control) (n = 6), anidulafungin at 5 mg/kg/day (AFG5) (n = 4), at 10 mg/kg/day (AFG10) (n = 4), voriconazole at 10 mg/kg/day q8h (VRC) (n = 4), anidulafungin-voriconazole combinations (AFG5+VRC) (n = 4), and (AFG10+VRC) (n = 4) treated rabbits. Animals treated with AFG5+VRC combination demonstrated significant resolution of pulmonary infiltrate volume in comparison to that of anidulafungin (*, P ≤ 0.05), and VRC (¶, P ≤ 0.01) alone.