. 2009 Mar 16;53(6):2266–2273. doi: 10.1128/AAC.01680-08

TABLE 2.

AUCs of resistant organisms by strain and concentration of second drug

Organism and concn of second drug	Mean AUC [mg·log₁₀ (CFU/ml)/liter] ± SD
Organism and concn of second drug	Wild-type isolate	MexAB pump-overexpressed mutant
Meropenem-resistant organism and tobramycin concn (mg/liter) of:
0	7.7 ± 1.67	57.6 ± 6.44^a
0.25	2.2 ± 0.20	28.7 ± 5.51^a
0.5	0.3 ± 0.46	7.1 ± 2.25^a
Tobramycin-resistant organism and meropenem concn (mg/liter) of:
0	17.9 ± 2.07	20.8 ± 0.32
0.5	5.6 ± 0.71	18.5 ± 2.25^a
1.0	2.2 ± 0.76	17.3 ± 1.89^a
2.0	0.7 + 1.23	10.8 + 2.59^a

P < 0.05.