TABLE 3.
Numbers of ampicillin resistance genes (blaTEM), expressed as percentages of the respective genomic DNA of the sample
| Day | Ampicillin group
|
P1A recombinant β-lactamase group
|
Ampicillin plus P1A recombinant β-lactamase group
|
|||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | Mean | SEM | Min | Max | Prevalence | n | Mean | SEM | Min | Max | Prevalence | n | Mean | SEM | Min | Max | Prevalence | |
| Baseline | 12 | 0 | 0 | 0 | 0.0006 | 1/12 | 12 | 0.0006 | 0.0006 | 0 | 0.0068 | 3/12 | 12 | 0.001 | 0.0007 | 0 | 0.0086 | 3/12 |
| Day 3 | 12 | 11.642a,b | 8.8986 | 0 | 107.49 | 8/12 | 12 | 0 | 0 | 0 | 0.0004 | 1/12 | 12 | 0.0014b | 0.0005 | 0 | 0.0047 | 5/12 |
| Day 4 | 11 | 7.8243b | 6.5669 | 0 | 74.085 | 5/11 | 12 | 0 | 0 | 0 | 0 | 0/12 | 12 | 0.0005b | 0.0004 | 0 | 0.0043 | 2/12 |
| Day 5 | 11 | 6.2559a,b | 5.5761 | 0 | 61.888 | 6/11 | 12 | 0 | 0 | 0 | 0.0004 | 1/12 | 12 | 0.0081b | 0.0066 | 0 | 0.0795 | 2/12 |
| Day 12 | 12 | 0.2392a | 0.2273 | 0 | 2.7377 | 6/12 | 12 | 0.0007 | 0.0006 | 0 | 0.0074 | 2/12 | 12 | 0.0084 | 0.0052 | 0 | 0.0569 | 3/12 |
There were statistically significant increases on day 3 (P < 0.008), day 5 (P < 0.03), and day 12 (P < 0.03).
There were statistically significant differences between the groups receiving ampicillin and ampicillin plus P1A recombinant β-lactamase on day 3 (P < 0.02), day 4 (P < 0.01), and day 5 (P < 0.01).