TABLE 3.
In vitro activities of formulations against L. major promastigotes and amastigotes
| Formulation | ED50 (μg/ml) for L. majora:
|
|
|---|---|---|
| Promastigotes | Amastigotes | |
| Lip-PM-10 | 65.32 ± 7.57b | 24.64 ± 1.51b |
| Lip-PM-15 | 59.73 ± 6.27b | 26.44 ± 1.89b |
| PM in solution | 205.70 ± 10.05 | 83.31 ± 16.65 |
| Control empty liposome | Inactive | Inactive |
a
The values are means ± standard deviations (n = 3).
b
There were statistically significant differences (P < 0.001) between the results for LPMFs and those for PM in solution.