FIG. 7.
(A) Nitric oxide levels in infected untreated control cells and omeprazole (Omep)-treated or bafilomycin A1 (Baf)-treated cells. Immunoblot signals of infected RAW264.7 cells for IκB-α at 20 or 40 min postinfection (p.i.) (B) or iNOS at 16 h postinfection (C) in the presence or absence of omeprazole are shown. β-Actin expression served as a loading control. (D) Levels of the secreted cytokines TNF-α and IL-6 in the supernatants 16 h postinfection in the untreated or omeprazole-treated samples. The statistical differences between NO and cytokine secretion were confirmed in a paired student's t test (*, P < 0.05; ***, P < 0.0005).