TABLE 1.

Modules in AbaR5

Regiona	Length (bp)	Progenitor				Region(s)/gene(s)	% Identity
		Name	Length (bp)	GenBank accession no.b	Part present (position, in bp)c
1	4,421	X	4,421	CP001182		top	100
2	7,322	Tn1696	16,318	U12338	8675-16318d	Δ3′-CS -IS6100-mer1696	100
3	5,157e	Tn1721	11,139	X61367f	5560-10727	ΔtnpA-tetR-tetA-pecM-ΔtnpA	99.7
4	154e	Tn21	19,672	AF071413	282-435	ΔtnpA	100
5	820	IS26	820	AY123253	Complete	IS26	100
6	2,883g	Tn1000	5,981	X60200	1-2883	ΔtnpA	74.9
7	685	Tn5393c	5,470	AF313472	2968-3652	ΔtnpR	99.9
8	820	IS26h	820	AY123253	Complete	IS26	100
9	175	IS26h	820	AY123253	645-820	ΔIS26	100
10	3,069	Tn6020	3,069	CT025832	1-3069	aphA1b
11	820	IS26	820	AY123253	Complete	IS26	100
12	446	Tn21	19,672	AF071413	3594-4039	ΔtnpM	100
13	1,371	5′-CSi	1,371	U12338	Complete	5′-CS	99.6
14	2,962	Cassettes	2,962	AF453999	1-2962	aacC1-orfP-orfP-orfQ-aadA1j	99.6
15	1,987	3′-CSi	2,239	U12338	1-1987	3′-CS	100
16	2,025	Y		CT025832k		resX-ΔtrbI
17	3,372	Tn6018l	3,372	AY128707	Complete	cadR-cadA-lspA-tnpA	96.7
18	4,003			CT025832k		ΔuspA-sup-orf4m

^aThe analysis begins with the first base of the multiple-antibiotic resistance region, i.e., after the left-hand Tn6018 in AbaR5.

^bAccession numbers used are either the earliest complete sequences or the complete and annotated sequences.

^cNumbering for IS is with the transposase gene from left to right; for class II Tn, the tnpA gene is on the left, except for Tn1721, which is as in X61367.

^dThe first base of this region corresponds to bp 391 of the 3′-CS, and AbaR5 lacks the partial copy of IS6100 (bp 11527 to 11974) in Tn1696.

^eRegions 3 and 4 overlap by 23 bp that are identical in Tn21 and Tn1721 and could be derived from either.

^fThis sequence has several single base differences and a short deletion which are not present in other published sequences of this region and might be errors in the Tn1721 complete sequence (X61367).

^gA portion (1,209 bp) was 99.6% identical to a partially sequenced Tn1000-like element found in GenBank accession no. AY598759.

^hPart of IS15.

ⁱ5′-CS and 3′-CS are the 5′ conserved segment and 3′ conserved segment, respectively, of a class 1 integron.

^jOpen reading frames orfP and orfQ have also been called orfX and orfX′, respectively.

^kFound only in A. baumannii strains AYE and ACICU.

^lWas described as ISPu12-like but is not an IS and was therefore renamed.

^msup (sulfate permease) is incorrectly labeled sul1 (sulfonamide-resistant dihydropteroate synthase) in previous publications (1, 6, 20); orf4 encodes an open reading frame of unknown function.

ⁿChromosomal gene found in A. baumannii strains AYE, ACICU, and ATCC 17978.