. 2009 Mar 16;77(6):2311–2319. doi: 10.1128/IAI.01298-08

TABLE 2.

Data for 47-kDa antigen epitopes in the trypsin domain identified by five patient sera

Protein	Position	Sequence homolog	ELISA optical density for:						Predicted epitope score^a
Protein	Position	Sequence homolog	Normal serum	Patient 201	Patient 202	Patient 211	Patient 215	Patient 252	Predicted epitope score^a
47 kDa	97	VTNENVIAGA	0.25	0.51	0.35	2.42	0.21	0.38	5.417
hHtrA1	216	VTNAHVVTNK
47 kDa	101	NVIAGAENIK	0.27	0.68	0.54	0.42	0.32	0.65	4.660
hHtrA1	220	HVVTNKHRVK
47 kDa	145	YATFGDSNQS	0.30	0.84	0.64	0.47	0.29	0.63	11.391
hHtrA1	264	VLLLGRSSEL
47 kDa	153	QSRVGDQVIA	0.21	0.52	0.51	0.31	0.18	0.24	7.607
hHtrA1	272	ELRPGEFVVA
47 kDa	165	SPFGLRGTVT	0.31	0.74	0.66	0.30	0.62	0.66	6.067
hHtrA1	284	SPFSLQNTVT
47 kDa	173	VTNGIISSKG	0.27	0.67	0.38	1.68	0.22	0.38	8.910
hHtrA1	292	VTTGIVSTTQ
47 kDa	177	IISSKGPDMG	0.30	1.11	0.74	0.51	0.49	0.76	9.916
hHtrA1	296	IVSTTQRGGK
47 kDa	193	FIQTNAAIHM	0.24	0.47	0.35	1.41	0.19	0.22	3.358
hHtrA1	312	YIQTDAIINY
47 kDa	201	HMGSFGGPMF	0.33	0.86	0.84	0.38	0.23	0.87	3.890
hHtrA1	320	NYGNSGGPLV
47 kDa	209	MFNLEGKIIG	0.26	0.44	0.71	0.25	0.20	0.38	4.419
hHtrA1	328	LVNLDGEVIG

Scores for continuous B-cell epitopes were predicted by using the BcePred server.