TABLE 1.
Experimental design showing numbers of mice of each genotype and infection status at necropsy time pointsa
| Expt no. | Mouse strain | Infection status | No. of mice at indicated WPI:
|
|||
|---|---|---|---|---|---|---|
| 6 | 12 | 24 | 36 | |||
| 1 | IL-10−/− | Sham | 5 | 5 | ND | ND |
| WTHc | 5 | 5 | ND | ND | ||
| cdtBHc mutant | 5 | 5 | ND | ND | ||
| 2 | IL-10−/− | Sham | 10 | 10 | 10 | 20 |
| WTHc | 10 | 10 | 10 | 20 | ||
| cdtBHc mutant | 10 | 10 | ND | ND | ||
| B6 | Sham | 10 | 10 | ND | ND | |
| WTHc | 10 | 10 | ND | ND | ||
| 3 | IL-10−/− | Sham | ND | 10 | ND | ND |
| WTHc | ND | 10 | ND | ND | ||
| cdtB-NHc mutant | ND | 10 | ND | ND | ||
a
Similar numbers of male and female mice were used in experiment 1, and exactly equivalent numbers of males and females were used in experiments 2 and 3. ND, not done.