Table 5.

AUC values for four major components of PPE in fasted dogs at 13 weeks in the 13-week follow-up dog study

		AUC (hr × ng/ml)
		FREE	TOTAL
EGCG	Lot A	29,191 ± 21,591	123,590 ± 123,330
	Lot B	45,160 ± 33,145	118,450 ± 91,381
	Lot C	41,189 ± 27582	123,760 ± 70,649
EGC	Lot A	2,144 ± 2,800	2,950 ± 3,434
	Lot B	1,765 ± 1,034	2,614 ± 995
	Lot C	1,887 ± 364	3,383 ± 1,213
ECG	Lot A	3,392 ± 4,321	9,071 ± 11,022
	Lot B	2,912 ± 2,190	6,663 ± 5,831
	Lot C	2,587 ± 1,449	7,354 ± 4,804
EC	Lot A	2820 ± 3843	5593 ± 6226
	Lot B	1,898 ± 768	4,517 ± 1,036
	Lot C	1,533 ± 209	5,877 ± 1,986

Lot A: 200 mg/kg/day (3846 mg/m²/day) PPE for 13 weeks to fasted dogs.

Lot B: 200 mg/kg/day (3862 mg/m²/day) PPE for 13 weeks to fasted dogs.

Lot C: 176 mg/kg/day (3416 mg/m²/day) PPE for 13 weeks to fasted dogs.

Values represent mean ± SD for n = 3.

AUC (0-last) where last = 24 hr.