Table 3.

Approximate levels of covalently bound radioactivity associated with target and non-target tissues after administration of naphthalene, 1-nitronaphthalene or 2-methylnaphthalene

Toxicant	Dose (mmoles/kg)	Lung (nmoles/mg protein)	Liver (nmoles/mg protein)
Naphthalenea	1.6	0.6	0.8
1-Nitronaphthaleneb	0.29	5.0	1.3
2-Methylnaphthalenec	2.8	0.6	1.5

Covalent binding data were derived from experiments conducted in susceptible rodent species (naphthalene and 2-methylnaphthalene-mice and 1-nitronaphthalene-rats) 2-4 hrs after intraperitoneal administration of a toxic dose of compound.

^adata taken from Buckpitt and Warren, 1983

^bdata taken from Wheelock et al., 2005; values were with samples obtained by lysis lavage

^cdata taken from Griffin et al., 1982