Table 1.
Characteristics of study population
| Total patients n (%) |
LEV patients n (% of arm) |
PHT patients n (% of arm) |
|
|---|---|---|---|
| Subjects enrolled | 29 (100) | 20 (69) | 9 (31) |
| Subjects with primary end-point follow-up | 23 (79) | 15 (75) | 8 (89) |
| Demographics | |||
| Female | 6 (26) | 6 (40) | 0 |
| Median age (range) | 45 (20–83) | 46 (20–56) | 39 (32–83) |
| Seizure type at presentation | |||
| Simple partial | 7 (30) | 6 (40) | 1 (13) |
| Complex partial | 5 (22) | 1 (7) | 4 (50) |
| Generalized | 11 (48) | 8 (53) | 3 (38) |
| Surgery | |||
| Craniotomy before study surgery | 7 (30) | 4 (27) | 3 (38) |
| Craniotomy for study | |||
| Gross total resection | 13 (56) | 10 (67) | 3 (38) |
| Subtotal resection | 10 (43) | 5 (33) | 5 (63) |
| Final tumor pathology | |||
| WHO grade 1 | |||
| DNET | 1 (4) | 1 (7) | 0 |
| WHO grade 2 | |||
| Astrocytoma | 3 (13) | 2 (13) | 1 (13) |
| Oligodendroglioma | 2 (9) | 1 (7) | 1 (13) |
| PXA | 1 (4) | 1 (7) | 0 |
| WHO grade 3 | |||
| Astrocytoma | 4 (17) | 4 (27) | 0 |
| Oligodendroglioma | 1 (4) | 0 | 1 (13) |
| Oligoastrocytoma | 2 (9) | 1 (7) | 1 (13) |
| WHO grade 4 | |||
| Glioblastoma | 9 (39) | 6 (40) | 3 (38) |
DNET dysembryoplastic neuroepithelial tumor; PXA pleomorphic xanthoastrocytoma; WHO World Health Organization (brain tumor grading scale)