Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2009 Jan 13;136(3):449–459. doi: 10.1242/dev.027599

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

PMC Copyright notice

Fig. 1. — The nopo phenotype. Representative syncytial embryos and mitotic spindles in embryos from wild-type or nopo^Z1447 females. (A,B) Staining of nopo-derived embryos reveals developmental arrest with condensed, unevenly spaced DNA (B) compared with wild type (A). (C-G) Microtubules are in green and DNA in red. (C) Wild-type spindle. (D-F) Shortened, barrel-shaped nopo spindles with detached centrosomes and misaligned chromosomes. Arrowheads indicate detached centrosomes out of focal plane; arrow, DNA at pole. Metaphase-like spindle with two centrosomes per pole (F) reveals an asynchrony of nuclear and centrosome cycles. (G) Similar defects are observed in an nopo^Exc142/Df(2R)Exel7153-derived embryo. (H-K) Microtubules are in green; centrosomes in blue. (H) Wild-type spindle. (I,J) nopo spindles with detached and/or missing centrosomes. (K) Tripolar nopo spindle. Scale bars: 20 μm.