Table 2.

Genes modulated as a consequence of CD146 downmodulation

Symbol	Accession number	Fold change	P value (t test)
DNA microarray
LIPG	[GenBank:NM_006033]	-6.75	0.02749
MCAM	[GenBank:NM_006500]	-3.61	0.00084
FPR1	[GenBank:NM_002029]	-2.88	0.03159
CYP1B1	[GenBank:NM_000104]	-2.73	0.03208
FN1	[GenBank:NM_212475]	-2.48	0.00657
SORCS2	[GenBank:NM_020777]	-2.17	0.0314
FLJ20160	[GenBank:NM_017694]	-1.74	0.01431
LTBP1	[GenBank:NM_206943]	-1.72	0.03606
HES1	[GenBank:NM_005524]	-1.7	0.04315
AIM1	[GenBank:NM_001624]	-1.63	0.00758
MFAP2	[GenBank:NM_002403]	-1.58	0.04437
HIPK2	[GenBank:NM_022740]	-1.55	0.00781
CALD1	[GenBank:NM_033138]	-1.51	0.0113
NAV1	[GenBank:NM_020443]	-1.5	0.00481
NFIC	[GenBank:NM_005597]	-1.5	0.0275
TGFBI	[GenBank:NM_000660]	-1.85*	0.03459
TRIM59	[GenBank:NM_173084]	-1.76*	0.01626
NFAT5	[GenBank:NM_138714]	-1.51*	0.04496
APCDD1L	[GenBank:NM_153360]	-2.38**	0.01035
GARNL4	[GenBank:NM_001100398]	-1.96**	0.04209
PCMTD1	[GenBank:NM_052937]	-1.59**	0.0362
Multiplex quantitative RT-PCR
KALRN	[GenBank:NM_003947]	-10	0.02973
PREX1	[GenBank:NM_020820]	-8.93	0.01711
VAV1	[GenBank:NM_005428]	-7.94	0.00688
FGD4	[GenBank:NM_139241]	-4.63	0.00318
RHOV	[GenBank:NM_133639]	-4.03	0.03116
CCL5	[GenBank:NM_002985]	-3.88	0.00536
ITGB3	[GenBank:NM_000212]	-3.61	0.00187
CXCL16	[GenBank:NM_022059]	-2.92	0.00252
THBS1	[GenBank:NM_003246]	-2.66	0.01279
CXCR4	[GenBank:NM_001008540]	-2.21	0.00259
ITGB4	[GenBank:NM_001005731]	-2.15	0.01068
CD44	[GenBank:NM_000610]	-1.92	0.00141
ITGA2	[GenBank:NM_002203]	-1.86	0.00191
ROCK2	[GenBank:NM_004850]	-1,80	0.00004
ITGA6	[GenBank:NM_000210]	-1.63	0.00274
VIM	[GenBank:NM_003380]	-1.45***	0.04761
ARHGEF11	[GenBank:NM_198236]	1.67	0.00288
BCL7A	[GenBank:NM_001024808]	1.69	0.02473
DEF6	[GenBank:NM_022047]	2.05	0.00946
TNK2	[GenBank:NM_005781]	2.18	0.00222
CXCL10	[GenBank:NM_001565]	2.51	0.03645

*Not validated by quantitative RT-PCR. **Quantitative RT-PCR not available.***Observed only with the TI6194 cell line.