Fig. 1.

Effect of [6]-gingerol on survival of BxPC-3 and HPAC cells. [6]-Gingerol inhibited growth of both BxPC-3 and HPAC cells in a dose-dependent manner. Cells were treated with different concentrations of [6]-gingerol. Control cells (empty circle) were treated with vehicle alone (0.1% DMSO). Cells were harvested at day 1, 3 and day 5 and cell viability was determined by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay as described in Materials and methods. Percent viability was calculated by comparison with controls. Values shown as the mean ± SEM obtained from four independent experiments.