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ATRA response of BM cells from PLZF–RARα and NPM–RARα transgenic mice. (A) Morphology of the cells treated 72 h in the absence (control) or presence of 1 μM ATRA. (B) Percentages of mature granulocytes (MG) and immature granulocytes (IMG) are shown at different time intervals with or without ATRA treatment. (Upper) BM cells from PLZF–RARα leukemic mouse no. 23. (Lower) BM cells from NPM–RARα mouse no. 7.
