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. 2009 May 27;25(12):i259–1267. doi: 10.1093/bioinformatics/btp196

Table 3.

Performance of the different methods for constrained GNA on the benchmark of (Bandyopadhyay et al., 2006) with second-order interactions added

Algorithm MRF IsoRank GA PATH
Number of conserved interactions 1112 1101 1140 1143
Number of HomoloGene pairs (121 cl.) 39 38 41 40
Number of HomoloGene pairs (602 cl.) 172 167 172 166
Timing (s) 623 31 372 1542

The number of recovered HomoloGene pairs is counting on the 121 Inparanoid clusters from the previous section as well as on the new 602 ambiguous Inparanoid clusters that have second-order interaction with other Inparanoid clusters.