Skip to main content
. 2009 May 27;25(12):i6–i14. doi: 10.1093/bioinformatics/btp222

Fig. 2.

Fig. 2.

Schematic illustration of a mixture estimation with and without constraints. (a) The algorithm starts with an initial guess of the mixture components. (b) After termination, the mixture optimally explains the data points. Instead of a hard assignment to the components, each data point has a posterior distribution over the components. (c and d) By including constraints (dashed arrows in green), the EM algorithm strives for an optimum that discriminates the negatively constrained data points.