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. 2009 May 27;25(12):i330–i338. doi: 10.1093/bioinformatics/btp228

Table 2.

Total calculation time in seconds (predicting secondary structures for 17 γ values of 850 RNA sequences) of the estimator appro3-1 for each δ and each combination of the probability distributions

δ pa-ct pa-mc pc-ct pc-mc
0 276 869 290 579 274 758 290 174
0.0001 16 471 5107 16 393 5009
0.001 7962 3202 7897 3124
0.01 3836 2130 3781 2065
0.1 2552 1600 2502 1541

We set α = 1/(|D| + 1) = 0.1 in this experiment. ‘x-y’ means appro3-1 with x of p(a) and y of p(s). pa, pc, mc and ct denote the ProbAlign model (Roshan and Livesay, 2006), the ProbCons model (Do et al., 2005), the McCaskill model (McCaskill, 1990) and the CONTRAfold model (Do et al., 2006a), respectively.