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. 1999 May 25;96(11):6330–6335. doi: 10.1073/pnas.96.11.6330

Figure 3.

Figure 3

mAb 4E4 identifies a subset of B6 NK cells that mediate CHO cell lysis. (A) mAb 4E4 reacts with a population of B6 but not BALB/c NK cells. Two-color flow cytometric analysis of naïve B6 and BALB/c splenocytes was performed with 4E4 and DX5 mAbs. (B) mAb 4E4-reactive cells mediate CHO lysis. Unseparated as well as FACS-sorted 4E4+ and 4E4 IL-2-activated B6 NK cells were assessed for their capacity to lyse CHO and YAC-1 targets alone or in the presence of either mAb 4E4 or anti-H-2Kb control mAb (E:T of 5:1).