Table 1.
Baseline characteristics by IL-18 9545 genotype
| 9545 TT | 9545 GT | 9545 GG | Total | p value | |
| Number (%) | 383 (58) | 225 (34) | 50 (8) | 658 | |
| Age (years) | 65 ± 1 | 66 ± 1 | 66 ± 1 | 66 ± 1 | 0.655 |
| Male sex (%) | 77 | 77 | 70 | 76 | 0.544 |
| Body mass index (kg/m2) | 28 ± 1 | 28 ± 1 | 26 ± 1 | 28 ± 1 | 0.022 |
| Ejection fraction (%) | 49.2 ± 0.7 | 48.8 ± 0.9 | 51.3 ± 2.1 | 49.3 ± 0.5 | 0.529 |
| Renal dysfunction (%) (Creatinine > 200 μmol/L) | 3.6 | 2.2 | 0.0 | 2.9 | 0.266 |
| Diabetes (Types I & II) (%) | 29 | 28 | 27 | 28 | 0.969 |
| Smoking (%) | 32 | 41 | 36 | 32 | 0.129 |
| Anti-hypertensive use (%) | 65 | 61 | 58 | 62 | 0.495 |
| Angiotensin-converting enzyme II inhibitor use (%) | 48 | 54 | 50 | 52 | 0.447 |
| Beta-blocker use (%) | 58 | 60 | 56 | 59 | 0.745 |
| Aspirin use (%) | 59 | 59 | 60 | 59 | 0.992 |
| Duration of surgery (hours) | 4.4 ± 0.1 | 4.5 ± 0.1 | 4.4 ± 0.1 | 4.5 ± 0.1 | 0.728 |
| Duration of bypass (hours) | 1.8 ± 0.1 | 1.9 ± 0.1 | 1.8 ± 0.1 | 1.8 ± 0.1 | 0.544 |
| Cross clamp time (hours) | 1.3 ± 0.1 | 1.4 ± 0.1 | 1.4 ± 0.1 | 1.4 ± 0.1 | 0.143 |
Continuous variables are reported as mean ± standard error of the mean.