Table 3.
Relationship between adiposity measures and risk of primary joint replacement by gender
| Females | Males | |||
| Variable | Hazard ratio (95% confidence interval) | P value | Hazard ratio (95% confidence interval) | P value |
| Weight, kg | ||||
| Q1 (F <59.7, M <73.0) | 1.00 | 1.00 | ||
| Q2 (F 59.7 to 66.2, M 73.0 to 79.7) | 1.84 (1.37 to 2.46) | 1.30 (0.93 to 1.80) | ||
| Q3 (F 66.2 to 74.6, M 79.7 to 87.4) | 2.69 (2.04 to 3.54) | 1.58 (1.15 to 2.16) | ||
| Q4 (F >74.6, M >87.4) | 4.12 (3.16 to 5.37) | 2.60 (1.93, 3.49) | ||
| Linear model (per 10 kg) | 1.42 (1.35 to 1.50) | <0.001 | 1.41 (1.31 to 1.52) | <0.001 |
| Body mass index, kg/m2 | ||||
| Q1 (F <23.2, M <24.7) | 1.00 | 1.00 | ||
| Q2 (F 23.2 to 25.9, M 24.7 to 26.8) | 1.85 (1.38 to 2.47) | 1.40 (1.00 to 1.97) | ||
| Q3 (F 25.9 to 29.3, M 26.8 to 29.2) | 2.68 (2.03 to 3.54) | 2.23 (1.63 to 3.06) | ||
| Q4 (F >29.3, M >29.2) | 3.87 (2.94 to 5.09) | 2.85 (2.08 to 3.90) | ||
| Linear model (per 5 kg/m2) | 1.55 (1.45 to 1.66) | <0.001 | 1.76 (1.56 to 1.98) | <0.001 |
| Waist circumference, cm | ||||
| Q1 (F <71.0, M <87.0) | 1.00 | 1.00 | ||
| Q2 (F 71.0 to 78.0, M 87.0 to 93.0) | 1.72 (1.29 to 2.28) | 1.45 (1.05 to 2.02) | ||
| Q3 (F 78.0 to 87.0, M 93.0 to 99.0) | 2.24 (1.70 to, 2.94) | 1.84 (1.33 to 2.53) | ||
| Q4 (F >87.0, M >99.0) | 3.03 (2.31 to 3.97) | 2.39 (1.76 to 3.24) | ||
| Linear model (per 10 cm) | 1.36 (1.27 to 1.44) | <0.001 | 1.41 (1.28 to 1.55) | <0.001 |
| Waist-to-hip ratio | ||||
| Q1 (F <0.74, M <0.88) | 1.00 | 1.00 | ||
| Q2 (F 0.74 to 0.78, M 0.88 to 0.92) | 1.25 (0.98 to 1.59) | 0.94 (0.69 to 1.29) | ||
| Q3 (F 0.78 to 0.82, M 0.92 to 0.96) | 1.25 (0.98 to 1.59) | 1.16 (0.86 to 1.57) | ||
| Q4 (F > 0.82, M > 0.96) | 1.32 (1.04 to 1.68) | 1.62 (1.22 to 2.15) | ||
| Linear model (per 0.1 unit) | 1.16 (1.03 to 1.30) | 0.01 | 1.36 (1.16 to 1.60) | <0.001 |
| Fat mass, kg | ||||
| Q1 (F <21.1, M <18.4) | 1.00 | 1.00 | ||
| Q2 (F 21.1 to 26.5, M 18.4 to 23.0) | 1.85 (1.38 to 2.49) | 1.53 (1.09 to 2.15) | ||
| Q3 (F 26.5 to 32.9, M 23.0 to 27.9) | 2.60 (1.96 to, 3.45) | 1.84 (1.33 to 2.55) | ||
| Q4 (F >32.9, M >27.9) | 4.04 (3.09 to 5.29) | 2.80 (2.06 to 3.81) | ||
| Linear model (per 10 kg) | 1.58 (1.47 to 1.69) | <0.001 | 1.69 (1.51 to 1.89) | <0.001 |
| Percentage fat, % | ||||
| Q1 (F <35.3, M <25.0) | 1.00 | 1.00 | ||
| Q2 (F 35.3 to 40.1, M 25.0 to 28.9) | 1.47 (1.11 to 1.96) | 1.43 (1.04 to 1.99) | ||
| Q3 (F 40.1 to 44.6, M 28.9 to 32.6) | 2.12 (1.62 to 2.77) | 1.51 (1.09 to 2.08) | ||
| Q4 (F >44.6, M >32.6) | 3.29 (2.55 to 4.24) | 2.56 (1.90 to 3.45) | ||
| Linear model (per 10%) | 1.99 (1.76 to 2.26) | <0.001 | 2.00 (1.67 to 2.39) | <0.001 |
All models adjusted for age, country of birth, and highest level of education. Linear models represent an approximate change of one standard deviation for each of the adiposity measures. Q1, first quartile; Q2, second quartile; Q3, third quartile; Q4, fourth quartile; F, female; M, male.